I've been having a lot of fun so far this ladder reset. This past weekend for example was the most fun I've had in a long time playing D2.... it was just super fun to have everyone starting from scratch and working together to progress through the game.
I remember running through A3 with a full party (in normal and nightmare) and realizing that I honestly can't remember the last time I EVER actually played through A3, and it was super fun.
Granted, I play on us west hardcore so there aren't a ton of players... but I've been able to get some pretty good games with real people. The only downsides I have seen with having bots on my realm have been:
1. The natural devaluation of items as others have stated
2. The trivialization of the ladder rankings (because bots will always have the top spots)
3. The acceleration of progression through the game (through the constant availability of bot baal games and increased availability of necessary progression items)
Overall I will say that bots haven't affected my personal enjoyment of the game too much. As a "legit" player (I only use jsp), I will say I have given up trying to even be on the top 16 of the ladder rankings which is kind of a bummer. But otherwise I still enjoy magic finding, finding those sweet upgrades, and helping my friends with items or rushes or whatever. I also enjoy the trading aspect very much, and if there was no jsp I would not be playing D2 today.