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d2jsp Forums > Off-Topic > General Chat > Homework Help > Cv Physiology > Bowditch Effect Vs. Ventricular Filling
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Jan 6 2019 03:38pm
Hiho,

As heart frequency increases, the Bowditch effect allows for increased contractility and thus increased cardiac output;
Meanwhile, the diastole is the phase shortened the most and therefore there is a lessened ventricular filling time with decreased ventricular filling per cycle. What should follow is a decrease in ventricular preload which will in turn lower contractility (Starling).

Empirically, we see our heart frequency increase as cardiac stress (i.e. exercise) increases, so obviously the first "overrules" the latter, but I wonder if anybody can explain the why and how of this phenomenon?


Rik
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Jan 10 2019 07:17am
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