Ever since Diablo 2, i just have always been against using sets. It seems the way the game is designed, you are forced to use them to progress into the high level rifts. I kind of think that i have hit a brick wall with my wizard. I can do speed runs at level 90-95 with no problems. I can consistently complete level 110 rifts, just not really fast. I put all my paragon into int and still very tanky. Im just looking for other ways to increase my damage. I keep learning new things every day about this game, like that follower can use oculus ring and i can receive benefit. I just learned that. Lol. I replaced %damage on my weapon with area damage and that helped a lot. If I could find other ways to increase my damage, that would be greatly appreciated!

Here are some things you might consider for wizard:
-Flavor of Time amulet on your follower doubles the duration of pylons for you
-stack elemental damage (whichever element type your main attack is) on your bracers and amulet
-augment your ancient gear with augment gems and topaz for increased intelligence (Caldesann’s Despair recipe in the cube)
-if you are meteor wizard, use the Star Pact rune (arcane element), it has the most damage output. Make sure to have as much crit chance and “crit hits restore arcane power” on your offhand, as well as use Conduit rune for Magic Weapon skill. You should try to get additional Arcane Power in the secondary slots on your gear as well to increase the max damage for Star Pact
-aim for 120-130% area damage total on char, and use Black Hole skill to group enemies before dropping meteor on them.
-area damage is great for clearing rifts, but eventually the Rift Guardian fights take too long, so make sure you are using Bane of the Stricken gem for pushing higher GR’s

Happy to take a look in game if you want other tips or pointers

Forgot to mention, the Legacy of Dreams gem is meant for non-set setups, so that is the biggest immediate damage boost if you’re not using it already. I assume you already are if you’re clearing 110’s though

There's actually a leaderboard for this, where you can look at the items and skills for the top players. The best solo GR for a Wizard with no set bonus this season is GR150 in 4:49, by [MST]LebronJames. He's playing a Legacy of Dreams Meteor build with 6/13 primals and completely maxed out gems, but even if you could use his gear, it obviously takes a ton of skill to pilot. He has a lot of different effects to keep track of, including the fact that any minor monster in a GR150 would 1-shot him.