Quote (Source 1)

Shoukhrat Mitalipov, an Oregon Health & Science University biologist, has successfully modified defective DNA in a human embryo using a technique called CRISPR. (The Oregonian/OregonLive)

Mitalipov's team worked with human embryos produced by sperm from men with a genetic mutation, the report said, noting they were of "clinical quality." They then modified the mutation using a gene-editing technique, CRISPR.

Chinese researchers have also modified human embryos with CRISPR. But the report said Mitalipov worked on more embryos and had more success. His team avoided altering genes that were not targeted -- called off-target effects -- or only modifying some of the targeted DNA, which is called mosaicism.

"Mitalipov and his colleagues are said to have convincingly shown that it is possible to avoid both mosaicism and 'off-target' effects, as the CRISPR errors are known," the report said.

Quote (Source 2)

For a number of years now we have had the ability to alter genetic material in a cell, using a technique called CRISPR.

The DNA that makes up our genome comprises long sequences of base pairs, each base indicated by one of four letters. These letters form a genetic alphabet, and the "words" or "sentences" created from a particular order of letters are the genes that determine our characteristics.

Sometimes words can be "misspelled" or sentences slightly garbled, resulting in a disease or disorder. Genetic engineering is designed to correct those mistakes. CRISPR is a tool that enables scientists to target a specific area of a gene, working like the search-and-replace function in Microsoft Word, to remove a section and insert the "correct" sequence.

In the last decade, CRISPR has been the primary tool for those seeking to modify genes – human and otherwise. Among other things, it has been used in experiments to make mosquitoes resistant to malaria, genetically modify plants to be resistant to disease, explore the possibility of engineered pets and livestock, and potentially treat some human diseases (including HIV, hemophilia and leukemia).

Quote (Saucisson6000 @ Jul 30 2017 06:56am)

Consider the risk of "edition" without have full controle.
Then consider, very simply, wrong side effects: only observable after 5 or 10 generations...

Potentially killing our specie... Im not dogmatizing but... Take care ! Be smart ! ^_^

Quote (Ep0ch @ 30 Jul 2017 12:57)

Yeah but the article says they are doing things like editing the genome of mosquitoes to make them resistance or immune to pathogens they are known to carry.
It's not limited to human type research only, how do you feel about those types of experiments?

Quote (ChivasRegal @ Jul 31 2017 03:40am)

:locked:

Quote (Saucisson6000 @ Jul 30 2017 11:37pm)

edit: the most fascinating example is monsanto with their roundup on one side and their resistant-to-roundup DNA that "accidentally" passed from culture plants to weeds.
Took several years... Acceptable when doing benefits...

Quote (DCSS @ Jul 30 2017 08:03am)

if i sent a CRISPR facility these schematics, some of my DNA, and a few million dollars do you think I'd get results?

http://i.imgur.com/b3S81BO.jpg

Quote (remco6 @ 31 Jul 2017 14:53)

Maybe it's just your English but you make it sound like the glyphosate resistance passed from the GMO plants to the weeds.
The restant weeds developed resistance by over use of round-up and would have developed the same resistance without GMO crops present.

Quote

The restant weeds developed resistance by over use of round-up and would have developed the same resistance without GMO crops present.