Quote (Paparick @ 22 Oct 2016 12:30)
Rerolling will not cause items to disappear.
There are only 2 ways to lose items
1 - die on Hard Core. You will lose whatever items the character is carrying at the time.
2 - deleting a character before items are removed to the vault or transferred to another character.
EDIT:
Sorry - there is a third way
You may accidentally shrine or trash an item that you need to use.
It has happened to a few of us on occasion -- it creates a strong "OH SHIT" moment
that third one is the worst!