That is some program you have running in the background, usually sort of anti virus, or even the actual malaware.
You have two options:
1- find out which program or process is doing it
2- run the game window mode (full screen)
Also another option you can try I don't promise it will work, but you can try , is running that game with desktop composition disabled.
You can find this option when you right click the game shortcut and go to properties.
This post was edited by FedOx on Jul 6 2015 05:34am