Quote (Balla @ Sep 23 2015 01:32pm)
Yeah
cba to find them now though
Really just a variety though. Seems to lower incidence of a variety of neurodegenerative and/or psychiatric conditions. Upregulates endogenous antioxidant production through like NRF2 and etc.. inducing a hormetic effect. Found to reduce the incidence of spontaneous DNA strand breaks by a good amount (20 some % IIRC). Induces hepatic lipophagy, basically to attenuate liver fat accretion, which is quite deleterious and a hallmark of metabolic syndrome. That finding has been found numerous times (diminishment of hepatic lipid accrual) via several different mechanisms too. One of late that I remember involved activating CREB (through PDE inhibition), which activated Sirt3, which activated AMPK. It in general ameliorates insulin sensitivity and increases fatty acid oxidation. Very ergogenic. Found to actually mitigate sarcopenia progression in mice. Through a wide variety of studies has shown correlation with increased longevity when consuming more coffee (3+ cups usually) and less morbidity. Etc etc really. Nectar of the gods.
did these studies involve straight caffeine? or coffee based?
i do caffeine pills instead of coffee. i take anywhere from 100 to 300 mg a day from just pill form. normally 100 to 200 mg before workout.