a few tips off the top of my head
-you need defenses. glass cannons don't work in this game. take a LOT of +life nodes (or energy shield nodes if you want to go chaos inoculation) in your passive tree.
-no specific class is the best. class does not determine your build at all other than your starting area on the tree, any class can use any ability. builds that are verified to be effective can be found on exilepro.com which Curse made in collaboration with Kripparian
-don't get too attached to your first character...you will likely screw it up, and the way respeccing works makes the game very alt-centric
-mobs in this game hit like trucks, but walk like snails and think like chickens. you should be kiting them around often (even as a melee) and not facetanking because they are very easy to manipulate but won't hesitate to smack you down if you take them head on
-flasks are an important part of your build. they're permanent items with consumable charges that will refill as you kill enemies. use them frequently but intelligently. they can be turned into blue items with affixes that are very helpful, so don't be afraid to spend transmute/augmentation/alteration orbs on them as a cheaper way to upgrade your character as opposed to buying or crafting gear.
-when you get to ledge (act 1), fellshrine (act 2), and the docks (act 3), use them to farm a few extra levels to keep your character ahead of the leveling curve
-hoard most of the currency/gems/yellows you find until you are knowledgeable enough to know their values
-read the affixes that blue/yellow mobs spawn with before you start fighting them, or right as you start. some of them can be dangerous and some of them can require a little more brainpower than others (e.g. 'other allies cannot die' aura where you have to kill the one mob or totem that is emitting the aura before anything nearby will die)
these threads on the official forums provide detailed information on the game mechanics and on the crafting system:
http://www.pathofexile.com/forum/view-thread/54003http://www.pathofexile.com/forum/view-thread/11707